Pattern Design in Progress

I've got a new sock design in progress.  This time, I've given myself the challenge of creating a design that can be knit in two sizes and worked either from the toe up or top down.  And just because that seemed entirely too simple, each foot is a mirrored pattern (left/right specific).  Essentially this design will be four patterns in one.  I'm working with techniques to make the patterns in such a manner that you can knit one sock toe up, the other top down, and have them appear as a proper match.  It's a fun challenge.

Do you have a directional preference when knitting socks?